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Article

West Nile Virus (WNV) Replication Is Independent of Autophagy in Mammalian Cells

21 Sept 2012

Abstract excerpt

Autophagy is a homeostatic process responsible for recycling cytosolic proteins and organelles. Moreover, this pathway contributes to the cell's intrinsic innate defenses. While many viruses have evolved mechanisms to antagonize the antiviral effects of the autophagy pathway, others subvert autophagy to facilitate replication. Here, we have investigated the role of autophagy in West Nile virus (WNV) replication....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 23029249
DOI: 10.1371/journal.pone.0045800

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