Hijacking autophagy for infection by flaviviruses

Abstract excerpt

• We summarize recent research progresses on hijacking of autophagy by flaviviruses. • Several typical flaviviridae (HCV,JEV,DENV,ZIKV,WNV) hijack autophagy for viral infection and defense against innate immunity. • The feasibility of using autophagy inhibitors for antiviral therapy is discussed. Autophagy is a lysosomal degradative pathway, which regulates the homeostasis of eukaryotic cells. This pathway can...

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