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Article

Modulation of invasive phenotype by interstitial pressure-driven convection in aggregates of human breast cancer cells.

PloS one - 1 Jan 2012

Tien Joe, Truslow James G, Nelson Celeste M

Abstract excerpt

This paper reports the effect of elevated pressure on the invasive phenotype of patterned three-dimensional (3D) aggregates of MDA-MB-231 human breast cancer cells. We found that the directionality of the interstitial pressure profile altered the frequency of invasion by cells located at the surf...

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Identifiers

PMID: 23028839
DOI: 10.1371/journal.pone.0045191
PMCID: PMC3445465

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23028839-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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