Article
Variation in genes related to cochlear biology is strongly associated with adult-onset deafness in border collies.
PLoS genetics - 1 Sept 2012
Yokoyama Jennifer S, Lam Ernest T, Ruhe Alison L, Erdman Carolyn A, Robertson Kathryn R, Webb Aubrey A, Williams D Colette, Chang Melanie L, Hytönen Marjo K, Lohi Hannes, Hamilton Steven P, Neff Mark W
Abstract excerpt
Domestic dogs can suffer from hearing losses that can have profound impacts on working ability and quality of life. We have identified a type of adult-onset hearing loss in Border Collies that appears to have a genetic cause, with an earlier age of onset (3-5 years) than typically expected for aging dogs (8-10 years). Studying this complex trait within pure breeds of dog may greatly increase our ability to...
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