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Article

A genome-wide association study of deafness in three canine breeds.

PloS one - 1 Jan 2020

Hayward Jessica J, Kelly-Smith Maria, Boyko Adam R, Burmeister Louise, De Risio Luisa, Mellersh Cathryn, Freeman Julia, Strain George M

Abstract excerpt

Congenital deafness in the domestic dog is usually related to the presence of white pigmentation, which is controlled primarily by the piebald locus on chromosome 20 and also by merle on chromosome 10. Pigment-associated deafness is also seen in other species, including cats, mice, sheep, alpacas, horses, cows, pigs, and humans, but the genetic factors determining why some piebald or merle dogs develop deafness...

Topics

Animals
Case-Control Studies
Deafness
Dog Diseases
Dogs
Evoked Potentials, Auditory
Genetic Loci
Genetic Predisposition to Disease
Genome-Wide Association Study
Hearing Tests
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Selective Breeding

Skin Pigmentation

Source

Open in PubMed Open full text

Identifiers

PMID: 32413090
DOI: 10.1371/journal.pone.0232900
PMCID: PMC7228063

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