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Article

Evidence of 5-HT components in human sperm: implications for protein tyrosine phosphorylation and the physiology of motility

2 Oct 2012

Abstract excerpt

Serotonin (5-hydroxytryptamine; C(10)H(12)N(2)O (5-HT)) is produced in the CNS and in some cells of peripheral tissues. In the mammalian male reproductive system, both 5-HT and tryptophan hydroxylase (TPH) have been described in Leydig cells of the testis and in principal cells of the caput epididymis. In capacitated hamster sperm, it has been shown that 5-HT promotes the acrosomal reaction. The aim of this work...

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PMID: 23028123
DOI: 10.1530/rep-12-0145

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