Article
Transforming growth factor-β3 intron 5 polymorphism as a screening marker for non-syndromic cleft lip with or without cleft palate.
Molecular medicine reports - 1 Dec 2012
Ulucan Korkut, Bayraktar Nazli, Parmaksiz Emine, Akcay Arzu, Güney Ahmet Ilter
Abstract excerpt
In this study, we evaluated the effect of transforming growth factor β3 intron 5 position +104 A➝G (TGF-β3 IVS5+104AG) transition in patients with a non-syndromic cleft lip with or without cleft palate (NSCL/P). A total of 68 patients and 114 controls were recruited for the study. A genotyping procedure was carried out using the PCR-RFLP method. For statistical analysis, the Chi-square test was used to compare...
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