Article
The Fanconi anemia pathway and Breast Cancer: A comprehensive review of clinical data.
Clinical breast cancer - 1 Jan 2022
Gianni Panagiota, Matenoglou Evangelia, Geropoulos Georgios, Agrawal Nirav, Adnani Harsha, Zafeiropoulos Stefanos, Miyara Santiago J, Guevara Sara, Mumford James M, Molmenti Ernesto P, Giannis Dimitrios
Abstract excerpt
The development of breast cancer depends on several risk factors, including environmental, lifestyle and genetic factors. Despite the evolution of DNA sequencing techniques and biomarker detection, the epidemiology and mechanisms of various breast cancer susceptibility genes have not been elucidated yet. Dysregulation of the DNA damage response causes genomic instability and increases the rate of mutagenesis and...
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