Article
Retained heterodisomy is associated with high gene expression in hyperhaploid inflammatory leiomyosarcoma.
Neoplasia (New York, N.Y.) - 1 Sept 2012
Nord Karolin H, Paulsson Kajsa, Veerla Srinivas, Wejde Johan, Brosjö Otte, Mandahl Nils, Mertens Fredrik
Abstract excerpt
Inflammatory leiomyosarcoma (ILMS) is a soft tissue tumor that morphologically resembles conventional leiomyosarcoma (LMS) admixed with a prominent inflammatory infiltrate. Genetic data on ILMS are still limited but have suggested that this entity is characterized by hyperhaploidy (24-34 chromosomes). This low chromosome number is otherwise uncommon in neoplasia and has been found only in 0.2% to 0.3% of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
