Bacterial Biosynthetic Gene Clusters Encoding the Anti-cancer Haterumalide Class of Molecules

Abstract excerpt

Haterumalides are halogenated macrolides with strong antitumor properties, making them attractive targets for chemical synthesis. Unfortunately, current synthetic routes to these molecules are inefficient. The potent haterumalide, oocydin A, was previously identified from two plant-associated bacteria through its high bioactivity against plant pathogenic fungi and oomycetes. In this study, we describe oocydin A...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genomics and Phylogenetic Studies
• Share to Microbial Natural Products and Biosynthesis
• Share to Plant-Microbe Interactions and Immunity