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The silver cation (Ag+): antistaphylococcal activity, mode of action and resistance studies

25 Sept 2012

Abstract excerpt

OBJECTIVES: To examine several poorly understood or contentious aspects of the antibacterial activity of silver (Ag(+)), including its cidality, mode of action, the prevalence of resistance amongst clinical staphylococcal isolates and the propensity for Staphylococcus aureus to develop Ag(+) resistance. METHODS: The effects of Ag(+) on the viability, macromolecular synthesis and membrane integrity of S. aureus...

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PMID: 23011288
DOI: 10.1093/jac/dks372

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