Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Redox-active compounds with a history of human use: antistaphylococcal action and potential for repurposing as topical antibiofilm agents.

The Journal of antimicrobial chemotherapy - 1 Feb 2015

Ooi N, Eady E A, Cove J H, O'Neill A J

Abstract excerpt

OBJECTIVES: To investigate the antistaphylococcal/antibiofilm activity and mode of action (MOA) of a panel of redox-active (RA) compounds with a history of human use and to provide a preliminary preclinical assessment of their potential for topical treatment of staphylococcal infections, including those involving a biofilm component. METHODS: Antistaphylococcal activity was evaluated by broth microdilution and by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Infective Agents, Local
Share to Biofilms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Bacterial

Share to Microbial Viability

Share to Oxidation-Reduction

Share to Staphylococcus

Share to Staphylococcus aureus

Share to Staphylococcus epidermidis

Source

Open in PubMed Open full text

Identifiers

PMID: 25368206
DOI: 10.1093/jac/dku409
PMCID: PMC4291238

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Redox-active compounds with a history of human use: antistaphylococcal action and potential for repurposing as topical antibiofilm agents.PMID 25368206Read ↗

Uncovering the mechanism of action of a historical antimicrobial against <i>S. aureus</i> and <i>A. baumannii</i>Semantic proximity Read ↗

Cutibacterium acnes inhibits Staphylococcus lugdunensis biofilm formation through inhibition of autolysis and purine biosynthesisSemantic proximity Read ↗

Celastrol mitigates staphyloxanthin biosynthesis and biofilm formation in Staphylococcus aureus via targeting key regulators of virulence; in vitro and in vivo approachSemantic proximity Read ↗

Disrupting Antimicrobial Resistance: Unveiling the Potential of Vitamin C in Combating Biofilm Formation in Drug-Resistant BacteriaSemantic proximity Read ↗

The silver cation (Ag+): antistaphylococcal activity, mode of action and resistance studiesSemantic proximity Read ↗

Terpenes Combinations Inhibit Biofilm Formation in <i>Staphyloccocus aureus</i> by Interfering with Initial AdhesionSemantic proximity Read ↗

Combinatorial Effects of Ursodeoxycholic Acid and Antibiotic in Combating Staphylococcus aureus Biofilm: The Roles of ROS and Virulence FactorsSemantic proximity Read ↗

Targeting Ocular Biofilms with Plant-Derived Antimicrobials in the Era of Antibiotic ResistanceSemantic proximity Read ↗

Manuka honey as a non-antibiotic alternative against Staphylococcus spp. and their small colony variant (SCVs) phenotypes.Semantic proximity Read ↗

Anti-virulence potential of iclaprim, a novel folic acid synthesis inhibitor, against Staphylococcus aureusSemantic proximity Read ↗

Eugenol Mediated Inhibition of Biofilm Formed by S. Aureus a Potent Organism for Pediatric Digestive System DiseasesSemantic proximity Read ↗

Repurposing of nucleoside- and nucleobase-derivative drugs as antibiotics and biofilm inhibitorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.