Article
Analysis of HLA-DRB3 alleles and supertypical genotypes in the MHC Class II region in sporadic inclusion body myositis.
Journal of neuroimmunology - 15 Jan 2013
Rojana-udomsart Arada, Mitrpant Chalermchai, James Ian, Witt Campbell, Needham Merrilee, Day Timothy, Kiers Lynette, Corbett Alastair, Martinez Patricia, Wilton Steve D, Mastaglia Frank L
Abstract excerpt
We compared the carriage frequencies of HLA-DRB3 and its major alleles and of HLA-DRB4 and HLA-DRB5 in an Australian sIBM cohort and a population control group who had previously been genotyped for the HLA-DRB1*03:01 risk allele. There was a strong disease association with the carriage of the DRB3*01:01 allele which was accounted for by its linkage disequilibrium with DRB1*03:01. The carriage of HLA-DRB4 was...
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