Article
Analysis of HLA class I and II alleles in sporadic inclusion-body myositis.
Journal of neurology - 1 Nov 2003
Lampe Johannes B, Gossrau Gudrun, Kempe Andrea, Füssel Monika, Schwurack Katja, Schröder Rolf, Krause Sabine, Kohnen Ralf, Walter Maggie C, Reichmann Heinz, Lochmüller Hanns
Abstract excerpt
Sporadic inclusion body myositis (s-IBM) is characterised by progressive weakness of proximal and distal limb muscles. Most patients are aged over 50 years at disease onset. Muscle biopsy reveals an inflammatory myopathy and cytoplasmic amyloid deposits. The mononuclear infiltrate is dominated by...
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