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Article

Impact of cytokine and cytokine receptor gene polymorphisms on cellular immunity after smallpox vaccination.

Gene - 15 Nov 2012

Ovsyannikova Inna G, Haralambieva Iana H, Kennedy Richard B, Pankratz V Shane, Vierkant Robert A, Jacobson Robert M, Poland Gregory A

Abstract excerpt

We explored associations between SNPs in cytokine/cytokine receptor genes and cellular immunity in subjects following primary smallpox vaccination. We also analyzed the genotype-phenotype associations discovered in the Caucasian subjects among a cohort of African-Americans. In Caucasians we found 277 associations (p<0.05) between gene SNPs and inter-individual variations in IFN-α, IL-12p40, IL-1β, IL-2, and TNF-α...

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Source

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Identifiers

PMID: 23009887
DOI: 10.1016/j.gene.2012.08.021
PMCID: PMC3463724

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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