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Article

Integrated analysis of genetic and proteomic data identifies biomarkers associated with adverse events following smallpox vaccination.

Genes and immunity - 1 Mar 2009

Reif D M, Motsinger-Reif A A, McKinney B A, Rock M T, Crowe J E, Moore J H

Abstract excerpt

Complex clinical outcomes, such as adverse reaction to vaccination, arise from the concerted interactions among the myriad components of a biological system. Therefore, comprehensive etiological models can be developed only through the integrated study of multiple types of experimental data. In this study, we apply this paradigm to high-dimensional genetic and proteomic data collected to elucidate the mechanisms...

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Identifiers

PMID: 18923431
DOI: 10.1038/gene.2008.80
PMCID: PMC2692715

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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