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Article

Evasion of tumours from the control of the immune system: consequences of brief encounters

25 Sept 2012

Abstract excerpt

BACKGROUND: In this work a mathematical model describing the growth of a solid tumour in the presence of an immune system response is presented. Specifically, attention is focused on the interactions between cytotoxic T-lymphocytes (CTLs) and tumour cells in a small, avascular multicellular tumour. At this stage of the disease the CTLs and the tumour cells are considered to be in a state of dynamic equilibrium or...

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PMID: 23009638
DOI: 10.1186/1745-6150-7-31

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