Article
Family-based designs.
IARC scientific publications - 1 Jan 2011
Amos Christopher I, Lange Christoph
Abstract excerpt
Family-based designs are used for a variety of reasons in genetic epidemiology, including the initial estimation of the strength of genetic effects for a disease, genetic linkage analysis by which genetic causes can be sublocalized to chromosomal regions, as well as to perform association studies that are not confounded by ethnic background. This chapter describes some of the approaches that are followed in the...
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