Article
Role of Helicobacter pylori cagA EPIYA motif and vacA genotypes for the development of gastrointestinal diseases in Southeast Asian countries: a meta-analysis.
BMC infectious diseases - 21 Sept 2012
Sahara Shu, Sugimoto Mitsushige, Vilaichone Ratha-Korn, Mahachai Varocha, Miyajima Hiroaki, Furuta Takahisa, Yamaoka Yoshio
Abstract excerpt
BACKGROUND: Infection with cagA-positive, cagA EPIYA motif ABD type, and vacA s1, m1, and i1 genotype strains of Helicobacter pylori is associated with an exacerbated inflammatory response and increased risk of gastroduodenal diseases. However, it is unclear whether the prevalence and virulence factor genotypes found in Southeast Asia are similar to those in Western countries. Here, we examined the cagA status...
Topics
- Antigens, Bacterial
- Asia, Southeastern
- Bacterial Proteins
- Genotype
- Helicobacter Infections
- Helicobacter pylori
- Humans
- Molecular Epidemiology
- Virulence Factors