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Mining and characterization of ubiquitin E3 ligases expressed in the mouse testis

19 Sept 2012

Abstract excerpt

BACKGROUND: Ubiquitin-mediated protein modification and degradation are believed to play important roles in mammalian spermatogenesis. The catalogues of ubiquitin activating enzymes, conjugating enzymes, and ligases (E3s) have been known for mammals such as mice and humans. However, a systematic characterization of E3s expressed during spermatogenesis has not been carried out. RESULTS: In present study, we set...

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PMID: 22992278
DOI: 10.1186/1471-2164-13-495

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