Article
Genetic and epigenetic factors in regulation of microRNA in colorectal cancers.
Methods (San Diego, Calif.) - 1 Jan 2013
Vinci Serena, Gelmini Stefania, Mancini Irene, Malentacchi Francesca, Pazzagli Mario, Beltrami Cristina, Pinzani Pamela, Orlando Claudio
Abstract excerpt
Studies on miRNA profiling revealed that a large number of them are significantly deregulated in human cancers. The molecular mechanisms of this deregulation are not totally clarified, even if genetics and epigenetics are frequently involved. Single nucleotide polymorphisms (SNPs) are the most co...
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