Article
MicroRNA gene polymorphisms and environmental factors increase patient susceptibility to hepatocellular carcinoma.
PloS one - 1 Jan 2014
Chu Yin-Hung, Hsieh Ming-Ju, Chiou Hui-Ling, Liou Yi-Sheng, Yang Chen-Chieh, Yang Shun-Fa, Kuo Wu-Hsien
Abstract excerpt
BACKGROUND: Micro RNAs (miRNAs) are small RNA fragments that naturally exist in the human body. Through various physiological mechanisms, miRNAs can generate different functions for regulating RNA protein levels and balancing abnormalities. Abnormal miRNA expression has been reported to be highly related to several diseases and cancers. Single-nucleotide polymorphisms (SNPs) in miRNAs have been reported to...
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