Article
Fatty liver reduces hepatitis B virus replication in a genotype B hepatitis B virus transgenic mice model.
Journal of gastroenterology and hepatology - 1 Dec 2012
Zhang Zheng, Pan Qin, Duan Xiao-Yan, Liu Qiang, Mo Guo-Yu, Rao Gui-Rong, Fan Jian-Gao
Abstract excerpt
BACKGROUND AND AIM: Non-alcoholic fatty liver disease (NAFLD) overlapping with chronic hepatitis B virus (HBV) infection is undergoing a rapid increase in China. Therefore, the establishment and character of an animal model with both NAFLD and chronic HBV infection has become an urgent task. METHODS: Mice with chronic HBV genotype B infection were established with a microinjection of oocytes. Transgenic and...
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