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Burkholdines from <i>Burkholderia ambifaria</i>: Antifungal Agents and Possible Virulence Factors

18 Sept 2012

Abstract excerpt

Burkholdines are cyclic lipopeptides with unusual antifungal potency, making them promising leads as a new class of antifungal agents. However, a recent report using knockout mutagenesis indicates that these and related compounds, such as occidiofungins, xylocandins, and cepacidines, may also be synonymous with the long-known hemolytic virulence factors found in diverse Burkholderia isolates. Because of their...

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PMID: 22988812
DOI: 10.1021/np300108u

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