<b><i>Francisella tularensis </i></b>Alters Human Neutrophil Gene Expression: Insights into the Molecular Basis of Delayed Neutrophil Apoptosis

Abstract excerpt

We demonstrated recently that <i>Francisella tularensis</i> profoundly impairs human neutrophil apoptosis, but how this is achieved is largely unknown. Herein we used human oligonucleotide microarrays to test the hypothesis that changes in neutrophil gene expression contribute to this phenotype, and now demonstrate that <i>F. tularensis</i> live vaccine strain (LVS) caused significant...

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