Article
Common genetic variants associated with disease from genome-wide association studies are mutually exclusive in prostate cancer and rheumatoid arthritis.
BJU international - 1 Jun 2013
Orozco Gisela, Goh Chee L, Al Olama Ali Amin, Benlloch-Garcia Sara, Govindasami Koveela, Guy Michelle, Muir Kenneth R, Giles Graham G, Severi Gianluca, Neal David E, Hamdy Freddie C, Donovan Jenny L, Kote-Jarai Zsofia, Easton Douglas F, Eyre Steve, Eeles Rosalind A
Abstract excerpt
UNLABELLED: WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: The link between inflammation and cancer has long been reported and inflammation is thought to play a role in the pathogenesis of many cancers, including prostate cancer (PrCa). Over the last 5 years, genome-wide association studies (GWAS) have reported numerous susceptibility loci that predispose individuals to many different traits. The...
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