Loss-of-function mutation in bi-functional marine bacterial sialyltransferase.

Abstract excerpt

An α2,3-sialyltransferase produced by Photobacterium phosphoreum JT-ISH-467 is a bi-functional enzyme showing both α2,3-sialyltransferase and α2,3-linkage specific sialidase activity. To date, the crystal structures of several sialyltransferases have been solved, but the roles of amino acid residues around the catalytic site have not been completely clarified. Hence we performed a mutational study using...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Aquatic Organisms
• Share to Catalytic Domain