Article
Rag1-/- mutant zebrafish demonstrate specific protection following bacterial re-exposure.
PloS one - 1 Jan 2012
Hohn Claudia, Petrie-Hanson Lora
Abstract excerpt
BACKGROUND: Recombination activation gene 1 deficient (rag1(-/-)) mutant zebrafish have a reduced lymphocyte-like cell population that lacks functional B and T lymphocytes of the acquired immune system, but includes Natural Killer (NK)-like cells and Non-specific cytotoxic cells (NCC) of the innate immune system. The innate immune system is thought to lack the adaptive characteristics of an acquired immune system...
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