Article
Characterization of rag1 mutant zebrafish leukocytes.
BMC immunology - 3 Feb 2009
Petrie-Hanson Lora, Hohn Claudia, Hanson Larry
Abstract excerpt
BACKGROUND: Zebrafish may prove to be one of the best vertebrate models for innate immunology. These fish have sophisticated immune components, yet rely heavily on innate immune mechanisms. Thus, the development and characterization of mutant and/or knock out zebrafish are critical to help define immune cell and immune gene functions in the zebrafish model. The use of Severe Combined Immunodeficient (SCID) and...
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