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Article

The association between severe obesity and characteristics of failed fertilized oocytes

11 Sept 2012

Abstract excerpt

STUDY QUESTION: Is the cytoskeletal and chromosomal organization of failed fertilized oocytes from severely obese patients (BMI ≥ 35 kg/m²) altered compared with that in patients with normal BMI (BMI 18.5-24.9 kg/m²)? SUMMARY ANSWER: Compared with normal BMI patients, severe obesity was associated with a greater prevalence of spindle anomalies and non-aligned chromosomes in failed fertilized oocytes. WHAT IS...

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PMID: 22968161
DOI: 10.1093/humrep/des308

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