Article
Plasma cytokines in polycythemia vera: phenotypic correlates, prognostic relevance, and comparison with myelofibrosis.
American journal of hematology - 1 Nov 2012
Vaidya Rakhee, Gangat Naseema, Jimma Thitina, Finke Christy M, Lasho Terra L, Pardanani Animesh, Tefferi Ayalew
Abstract excerpt
Plasma cytokine milieu is abnormal in primary myelofibrosis (PMF) and correlates with disease phenotype and prognosis. In this study, we show that several plasma cytokines are also abnormally expressed in polycythemia vera (PV; n = 65), compared to normal controls (n = 35), but with a significantly different pattern than that of PMF (n = 127). Direct phenotypic correlation in PV included levels of IL-12 with...
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