Article
Loss of zygotic NUP107 protein causes missing of pharyngeal skeleton and other tissue defects with impaired nuclear pore function in zebrafish embryos.
The Journal of biological chemistry - 2 Nov 2012
Zheng Xiaofeng, Yang Shuyan, Han Yanchao, Zhao Xinyi, Zhao Long, Tian Tian, Tong Jingyuan, Xu Pengfei, Xiong Cong, Meng Anming
Abstract excerpt
The Nup107-160 multiprotein subcomplex is essential for the assembly of nuclear pore complexes. The developmental functions of individual constituents of this subcomplex in vertebrates remain elusive. In particular, it is unknown whether Nup107 plays an important role in development of vertebrate embryos. Zebrafish nup107 is maternally expressed and its zygotic expression becomes prominent in the head region and...
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