Article
Pseudomonas aeruginosa syntrophy in chronically colonized airways of cystic fibrosis patients.
Antimicrobial agents and chemotherapy - 1 Nov 2012
Qin Xuan, Zerr Danielle M, McNutt Michael A, Berry Jessica E, Burns Jane L, Kapur Raj P
Abstract excerpt
Pseudomonas aeruginosa isolates from cystic fibrosis (CF) patients undergo remarkable phenotypic divergence over time, including loss of pigmentation, hemolysis, motility, and quorum sensing and emergence of antibiotic hypersusceptibility and/or auxotrophism. With prolonged antibiotic treatment and steady decline in lung function in chronically infected patients, the divergent characteristics associated with CF...
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