Article
TaqMan real-time polymerase chain reaction for detection of SEC1-FUT2 hybrid alleles: identification of novel hybrid allele.
Clinica chimica acta; international journal of clinical chemistry - 16 Jan 2013
Soejima Mikiko, Koda Yoshiro
Abstract excerpt
BACKGROUND: Two hybrid alleles between the secretor type α(1,2)fucosyltransferase gene (FUT2) and a pseudogene of FUT2 (SEC1) have been reported so far; parts of the SEC1 and FUT2 sequences are suggested to be susceptible to recombination. The se(fus), one of the two hybrid alleles, is found in Japanese populations at relative high frequencies. METHODS: A TaqMan assay to distinguish SEC1 and SEC1-FUT2 hybrid...
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