Article
Sec1-FUT2-Sec1 hybrid allele generated by interlocus gene conversion.
Transfusion - 1 Mar 2008
Soejima Mikiko, Fujihara Junko, Takeshita Haruo, Koda Yoshiro
Abstract excerpt
BACKGROUND: Many single-nucleotide polymorphisms have been identified in the coding region of the FUT2 locus, which encodes secretor type alpha(1,2)fucosyltransferase. In addition, three recombination alleles have been reported. Of these recombination alleles, a fusion gene generated by an unequal crossing over between Sec1, a pseudogene that locates 23 kb upstream to and has high sequence homology with FUT2 and...
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