Article
A microfluidic system for long-term time-lapse microscopy studies of mycobacteria.
Tuberculosis (Edinburgh, Scotland) - 1 Nov 2012
Golchin Solmaz A, Stratford James, Curry Richard J, McFadden Johnjoe
Abstract excerpt
Phenotypic heterogeneity in bacterial populations is thought to contribute to a number of important phenomena including sporulation and persistence. The latter has clinical implications in many diseases such as tuberculosis, where persistence of Mycobacterium tuberculosis within the human host is believed to be the root cause of latent tuberculosis and the ability of a minority population of cells to survive...
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