Article
Creation of an open-access, mutation-defined fibroblast resource for neurological disease research.
PloS one - 1 Jan 2012
Wray Selina, Self Matthew, Lewis Patrick A, Taanman Jan-Willem, Ryan Natalie S, Mahoney Colin J, Liang Yuying, Devine Michael J, Sheerin Una-Marie, Houlden Henry, Morris Huw R, Healy Daniel, Marti-Masso Jose-Felix, Preza Elisavet, Barker Suzanne, Sutherland Margaret, Corriveau Roderick A, D'Andrea Michael, Schapira Anthony H V, Uitti Ryan J, Guttman Mark, Opala Grzegorz, Jasinska-Myga Barbara, Puschmann Andreas, Nilsson Christer, Espay Alberto J, Slawek Jaroslaw, Gutmann Ludwig, Boeve Bradley F, Boylan Kevin, Stoessl A Jon, Ross Owen A, Maragakis Nicholas J, Van Gerpen Jay, Gerstenhaber Melissa, Gwinn Katrina, Dawson Ted M, Isacson Ole, Marder Karen S, Clark Lorraine N, Przedborski Serge E, Finkbeiner Steven, Rothstein Jeffrey D, Wszolek Zbigniew K, Rossor Martin N, Hardy John
Abstract excerpt
Our understanding of the molecular mechanisms of many neurological disorders has been greatly enhanced by the discovery of mutations in genes linked to familial forms of these diseases. These have facilitated the generation of cell and animal models that can be used to understand the underlying m...
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