Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

German populations with infrequent CHEK2*1100delC and minor associations with early-onset and familial breast cancer.

European journal of cancer (Oxford, England : 1990) - 1 Dec 2005

Rashid Muhammad U, Jakubowska Anna, Justenhoven Christina, Harth Volker, Pesch Beate, Baisch Christian, Pierl Christiane B, Brüning Thomas, Ko Yon, Benner Axel, Wichmann Heinz-Erich, Brauch Hiltrud, Hamann Ute

Abstract excerpt

CHEK2*1100delC is associated with a twofold increased breast cancer risk. This was shown in a collaborative analysis of European populations, but not in other populations from Europe and the US. Accordingly, there is a need to clarify the role of CHEK2*1100delC in breast cancer. We established its prevalence in two German populations GENICA (Northrhine-Westphalia, n = 724) and KORA (Bavaria, n = 600) and in women...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes, BRCA2
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Checkpoint Kinase 2

Share to Genes, BRCA1

Share to Germany

Share to Pedigree

Share to Prevalence

Share to Protein Serine-Threonine Kinases

Source

Identifiers

PMID: 16239104
DOI: 10.1016/j.ejca.2005.04.049

Genes

CHEK2
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

German populations with infrequent CHEK2*1100delC and minor associations with early-onset and familial breast cancer.PMID 16239104Read ↗

CHEK2 c.1100delC allele is rarely identified in Greek breast cancer cases.Semantic proximity Read ↗

Limited relevance of the CHEK2 gene in hereditary breast cancer.Semantic proximity Read ↗

CHEK2 1100delC variant and breast cancer risk in Caucasians: a meta-analysis based on 25 studies with 29,154 cases and 37,064 controls.Semantic proximity Read ↗

CHEK2 1100delC is prevalent in Swedish early onset familial breast cancer.Semantic proximity Read ↗

CHEK2*1100delC homozygosity in the Netherlands--prevalence and risk of breast and lung cancer.Semantic proximity Read ↗

Cohort profile: a nationwide study in Dutch CHEK2 c.1100delC families using the infrastructure of the HEreditary Breast and Ovarian cancer study Netherlands - Hebon-CHEK2.Semantic proximity Read ↗

CHEK2*1100delC genotyping for clinical assessment of breast cancer risk: meta-analyses of 26,000 patient cases and 27,000 controls.Semantic proximity Read ↗

Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers.Semantic proximity Read ↗

CHEK2 1100DELC germline mutation: a frequency study in hereditary breast and colon cancer Brazilian families.Semantic proximity Read ↗

Absence of CHEK2*1100delC mutation in families with hereditary breast cancer in North America.Semantic proximity Read ↗

A search for modifying genetic factors in CHEK2:c.1100delC breast cancer patients.Semantic proximity Read ↗

Frequency of the CHEK2 1100delC mutation among women with breast cancer: an international study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.