Article
Undifferentiated acute leukemia and lineage infidelity (difficulties in classification and management).
Medical and pediatric oncology - 1 Jan 1990
DeLaat C A, Files B, Harris R E, Neudorf S, Lampkin B C
Abstract excerpt
The acute leukemias have been considered to represent a clonal expansion of a malignant transformed hematopoietic progenitor cell with adherence to either the myeloid or lymphoid lineage--"lineage fidelity." Lineage fidelity has been challenged by the demonstration of lineage switching or mixed-lineage leukemias. We describe a 7 year old male who presented with undifferentiated acute leukemia and nasopharyngeal...
Topics
- Burkitt Lymphoma
- Child
- Cytogenetics
- Diagnosis, Differential
- Humans
- Leukemia, B-Cell
- Leukemia, Biphenotypic, Acute
- Leukemia, Myeloid, Acute
- Male
- Neoplasm Recurrence, Local
- Phenotype