Accumulation of neutral mutations in growing cell colonies with competition.

Abstract excerpt

Neutral mutations play an important role in many biological processes including cancer initiation and progression, the generation of drug resistance in bacterial and viral diseases as well as cancers, and the development of organs in multicellular organisms. In this paper we study how neutral mutants are accumulated in nonlinearly growing colonies of cells subject to growth constraints such as crowding or lack of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cell Division
• Share to Cell Proliferation
• Share to Epithelial Cells