Article
Association between Rho-kinase (ROCK2) gene polymorphisms and Behçet's disease.
Translational research : the journal of laboratory and clinical medicine - 1 Dec 2012
Oguz Elif, Alasehirli Belgin, Pehlivan Yavuz, Onat Ahmet Mesut, Oztuzcu Serdar, Ozkara Esma, Kisacik Bünyamin, Camci Celaletdin, Demiryürek Abdullah T
Abstract excerpt
Behçet's disease (BD) is a multi-systemic vasculitis. The aim of this study was to investigate the association between Rho-kinase (ROCK2) gene polymorphisms and patients with BD in a Turkish population. A total of 194 BD patients and 276 healthy controls with similar age and sex were included to this study. Polymorphisms were analyzed in genomic DNA using a BioMark 96.96 dynamic array system. mRNA from blood...
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