Article
Activation of PDGFR and EGFR promotes the acquisition of a stem cell-like phenotype in schwannomas.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology - 1 Dec 2012
Yi David, Kuo Selena Z, Zheng Hao, Abhold Eric L, Brown Carrie Maiorana, Doherty Joni K, Wang-Rodriguez Jessica, Harris Jeffery P, Ongkeko Weg M
Abstract excerpt
OBJECTIVES: Vestibular schwannomas (VS) are benign tumors that arise from unregulated growth of Schwann cells. Both benign and malignant tumors are believed to contain tumor stem cells that are hypothesized to originate from dysregulation of tumor suppressors and oncogenes. We aimed to determine...
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