Article
A probabilistic model for cell population phenotyping using HCS data.
PloS one - 1 Jan 2012
Pauwels Edouard, Surdez Didier, Stoll Gautier, Lescure Aurianne, Del Nery Elaine, Delattre Olivier, Stoven Véronique
Abstract excerpt
High Content Screening (HCS) platforms allow screening living cells under a wide range of experimental conditions and give access to a whole panel of cellular responses to a specific treatment. The outcome is a series of cell population images. Within these images, the heterogeneity of cellular response to the same treatment leads to a whole range of observed values for the recorded cellular features....
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