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Article

Serum Response Factor (SRF)-cofilin-actin signaling axis modulates mitochondrial dynamics.

Proceedings of the National Academy of Sciences of the United States of America - 18 Sept 2012

Beck Henning, Flynn Kevin, Lindenberg Katrin S, Schwarz Heinz, Bradke Frank, Di Giovanni Simone, Knöll Bernd

Abstract excerpt

Aberrant mitochondrial function, morphology, and transport are main features of neurodegenerative diseases. To date, mitochondrial transport within neurons is thought to rely mainly on microtubules, whereas actin might mediate short-range movements and mitochondrial anchoring. Here, we analyzed t...

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Identifiers

PMID: 22927399
DOI: 10.1073/pnas.1208141109
PMCID: PMC3458318

Genes

SRF
HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22927399-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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