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As Clear as Mud? Determining the Diversity and Prevalence of Prophages in the Draft Genomes of Estuarine Isolates of Clostridium difficile.

Genome biology and evolution - 27 May 2015

Hargreaves Katherine R, Otieno James R, Thanki Anisha, Blades Matthew J, Millard Andrew D, Browne Hilary P, Lawley Trevor D, Clokie Martha R J

Abstract excerpt

The bacterium Clostridium difficile is a significant cause of nosocomial infections worldwide. The pathogenic success of this organism can be attributed to its flexible genome which is characterized by the exchange of mobile genetic elements, and by ongoing genome evolution. Despite its pathogenic status, C. difficile can also be carried asymptomatically, and has been isolated from natural environments such as...

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PMID: 26019165
DOI: 10.1093/gbe/evv094
PMCID: PMC4524475

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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