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Morphological and genetic diversity of temperate phages in Clostridium difficile.

Applied and environmental microbiology - 1 Nov 2007

Fortier Louis-Charles, Moineau Sylvain

Abstract excerpt

Eight temperate phages were characterized after mitomycin C induction of six Clostridium difficile isolates corresponding to six distinct PCR ribotypes. The hypervirulent C. difficile strain responsible for a multi-institutional outbreak (NAP1/027 or QCD-32g58) was among these prophage-containing strains. Observation of the crude lysates by transmission electron microscopy (TEM) revealed the presence of three...

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Bacterial Toxins
Blotting, Southern
Clostridioides difficile
Genome, Viral
Microscopy, Electron, Transmission

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PMID: 17890338
DOI: 10.1128/AEM.00582-07
PMCID: PMC2168219

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