Article
Long-term colonization of the cystic fibrosis lung by Burkholderia cepacia complex bacteria: epidemiology, clonal variation, and genome-wide expression alterations.
Frontiers in cellular and infection microbiology - 1 Jan 2011
Coutinho Carla P, Dos Santos Sandra C, Madeira Andreia, Mira Nuno P, Moreira Ana S, Sá-Correia Isabel
Abstract excerpt
Long-term respiratory infections with Burkholderia cepacia complex (Bcc) bacteria in cystic fibrosis (CF) patients generally lead to a more rapid decline in lung function and, in some cases, to a fatal necrotizing pneumonia known as the "cepacia syndrome." Bcc bacteria are ubiquitous in the environment and are recognized as serious opportunistic pathogens that are virtually impossible to eradicate from the CF...
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