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Article

Applying microsatellite multiplex PCR analysis (MMPA) for determining allele copy-number status and percentage of normal cells within tumors.

PloS one - 1 Jan 2012

Garcia-Linares Carles, Mercadé Jaume, Gel Bernat, Biayna Josep, Terribas Ernest, Lázaro Conxi, Serra Eduard

Abstract excerpt

The study of somatic genetic alterations in tumors contributes to the understanding and management of cancer. Genetic alterations, such us copy number or copy neutral changes, generate allelic imbalances (AIs) that can be determined using polymorphic markers. Here we report the development of a s...

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PMID: 22916147
DOI: 10.1371/journal.pone.0042682
PMCID: PMC3419736

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22916147-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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