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Article

NOL11, implicated in the pathogenesis of North American Indian childhood cirrhosis, is required for pre-rRNA transcription and processing.

PLoS genetics - 1 Jan 2012

Freed Emily F, Prieto José-Luis, McCann Kathleen L, McStay Brian, Baserga Susan J

Abstract excerpt

The fundamental process of ribosome biogenesis requires hundreds of factors and takes place in the nucleolus. This process has been most thoroughly characterized in baker's yeast and is generally well conserved from yeast to humans. However, some of the required proteins in yeast are not found in humans, raising the possibility that they have been replaced by functional analogs. Our objective was to identify...

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Source

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Identifiers

PMID: 22916032
DOI: 10.1371/journal.pgen.1002892
PMCID: PMC3420923

Genes

NOL11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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