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Article

Differential weight-loss responses of APOA2 genotype carriers to low-carbohydrate and low-fat diets: the DIETFITS trial.

Obesity (Silver Spring, Md.) - 1 Jun 2025

Lai Chao-Qiang, Parnell Laurence D, Das Sai Krupa, Gardner Christopher D, Ordovás José M

Abstract excerpt

OBJECTIVE: This study aimed to determine whether APOA2 genotypes and saturated fatty acid (SAT) intake affect weight-loss response to healthy low-carbohydrate (HLC) and healthy low-fat (HLF) diets. METHODS: This is a secondary analysis of the Diet Intervention Examining The Factors Interacting with Treatment Success (DIETFITS) study, a 12-month randomized clinical trial of HLC or HLF diets in 609 adults aged 18...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40310284
DOI: 10.1002/oby.24288
PMCID: PMC12276828

Genes

APOA2
HLF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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